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上海研盟生物科技有限公司
上海研盟生物科技有限公司
研盟生物標記抗體“Anti-Bim/FITC,FITC標記的細胞死亡調解子抗體"，規格100ul，保證品質，咨詢：
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產品名稱：Anti-Bim/FITC,FITC標記的細胞死亡調解子抗體
產品編號：BYK-1488R-FITC
英文名稱 Anti-Bim/FITC
中文名稱 FITC標記的細胞死亡調解子抗體
別 名 Bcl-2 interacting mediator of cell death; Bcl-2-like protein 11; Bcl2-L-11; Bcl2-interacting mediator of cell death; BCL2L11; BAM; BIM; BIM-alpha6; BIM-beta6; BIM-beta7; BimEL; BimL; BOD.
研究領域 細胞生物 神經生物學 細胞凋亡 激酶和磷酸酶
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
產品應用 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
細胞定位 細胞膜
性 狀 Lyophilized or Liquid
濃 度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from the middle of human Bim
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-Bim/FITC,FITC標記的細胞死亡調解子抗體產品介紹：Background: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.
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