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上海研盟生物科技有限公司
上海研盟生物科技有限公司
研盟生物標記抗體“Anti-CIDEB/FITC,FITC標記的CIDEB抗體“，規格100ul，保證品質，咨詢：
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產品名稱：Anti-CIDEB/FITC,FITC標記的CIDEB抗體
產品編號：BYK-0716R-FITC
英文名稱 Anti-CIDEB/FITC
中文名稱 FITC標記的CIDEB抗體
別 名 cell death activator CIDE-B; Cell death activator CIDE B; Cell death inducing DFFA like effector B; CIDEB_HUMAN; cell death-inducing DFFA-like effector B; Cide-b.
研究領域 腫瘤 細胞生物 染色質和核信號 細胞凋亡 細胞周期蛋白
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse,
產品應用 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性 狀 Lyophilized or Liquid
濃 度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CIDEB (115-160aa)
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-CIDEB/FITC,FITC標記的CIDEB抗體產品介紹：Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as an inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE A and CIDE B were recently identified. CIDE contains a new type of domain termed CIDE N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE B induces apoptosis, which is inhibited by DFF45. CIDE B is a DFF45 inhibitable effector that promotes cell death and DNA fragmentation. CIDE B is expressed mainly in liver and small intestine and at lower levels in spleen, colon, kidney, peripheral blood lymphocytes, and bone marrow.
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