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研盟生物標記抗體“Anti-HPV16 E7/FITC,FITC標記的人類乳tou狀瘤病毒16-E7抗體“,規格100ul,保證品質,咨詢:
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產品名稱 Anti-HPV16 E7/FITC,FITC標記的人類乳tou狀瘤病毒16-E7抗體
產品編號 BYK-0992R-FITC
英文名稱 Anti-HPV16 E7/FITC
中文名稱 FITC標記的人類乳tou狀瘤病毒16-E7抗體
別 名 E7; HPV16 E7 protein; Human Papilloma Virus; Human papillomavirus type 16 E7; Human papillomavirus type 16 E7; Protein E7; Human Papillomavirus 16 (E7); HPV16 E7; E7 protein (HPV16); VE7_HPV16; HPV16-E7.
研究領域 腫瘤 免疫學 細菌及病毒
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 HPV16
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 11kDa
性 狀 Lyophilized or Liquid
濃 度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from the middle of HPV16-E7
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-HPV16 E7/FITC,FITC標記的人類乳tou狀瘤病毒16-E7抗體產品介紹:Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximay 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro.
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