研究領(lǐng)域 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞膜受體 抗體來源 Rabbit 克隆類型 Polyclonal 交叉反應(yīng) Human, Mouse, Rat, 產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量 99kDa 細(xì)胞定位 細(xì)胞膜 性 狀 Lyophilized or Liquid 濃 度 1mg/ml 免 疫 原 KLH conjugated synthetic peptide derived from human IL6R beta
亞 型 IgG 純化方法 affinity purified by Protein A 儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-CD130/FITC,FITC標(biāo)記的白細(xì)胞介素6受體β抗體IL-6Rβ產(chǎn)品介紹:CD130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.