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武漢紐斯特生物科技有限公司
武漢紐斯特生物科技有限公司
Anti ErbB2(V777A) mouse monoclonal Antibody
ErbB2(V777A) [26080]
[100 µL]
| Catalog Number: 26080 |
| Gene Symbol: ERBB2/HER2/Neu |
| Description: Anti ErbB2(V777A) mouse monoclonal Antibody |
| Background: The ErbB family is composed of four plasma membrane-bound receptor tyrosine kinases. Amplification or over-expression of the ERBB2 gene occurs in approximately 30% of breast cancers. HER2 is encoded by ERBB2, a known proto-oncogene located at the long arm of human chromosome 17(17q21-q22). HER2 proteins have been shown to form clusters in cell membranes that may play a role in tumorigenesis. Mutations of ErbB2 protein, including V777A, have been indicated in human cancers. |
| Immunogen: A synthetic peptide surround the 777A codon of ErbB2 protein. |
| Tested Applications: ELISA, WB, IF, IHC |
| Recommended Dilutions: ELISA: 1:500-1:5000 WB: 1:200-1:2000 IF: 1:100 IHC: 1:50-1:100 |
| Concentration: 0.2 mg/ml |
| Host: mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: |
| Purity: Purified from ascites |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ ａnd Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes V777A mutant but not wild type ErbB2 protein, of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles. |
| Download Datasheet: |
| Immunofluorescence: |
| Immunofluorescence of cells expressing ErbB2 proteins with Anti ErbB2(V777A) antibody. HEK293T cells were transfected with pCDNA3-GFP ErbB2 WT plasmid (left column) or pCDNA3-GFP ErbB2(V777A) plasmid (right column), then fixed and stained with Anti ErbB2(V777A) monoclonal antibody (Cat. #26080). |
| Related Products | |||
| Catalog# | Name | Size | Price |
| Anti ERBB2 Rabbit polyclonal Antibody | 100 μL | ￥2600 | |
| Anti ERBB2 Rabbit Polyclonal Antibody | 100 μL | ￥2600 | |
| Anti ERBB2(V777A) mouse monoclonal Antibody | 100 μL | ￥4800 | |
| Anti ERBB2 mouse monoclonal Antibody | 100 μL | ￥2800 | |
| Anti ERBB2(D769Y) Mouse Monoclonal Antibody | 100 μL | ￥4800 | |
| Anti ERBB2(D769H) Mouse Monoclonal Antibody | 100 μL | ￥4800 |
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