GNAQ(Q209R)[26330][100ul]CatalogNumber:26330GeneSymbol:GNAQ,CMC1,G-ALPHA-q,GAQ,SWSDescription:AntiGNAQ(Q209R)MouseMonoclonalAntibodyBackground:GNAQisaproteinthatinhumansencodedbytheGNAQgene

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GNAQ(Q209R) [26330]
[100ul]

Catalog Number: 26330

Gene Symbol: GNAQ, CMC1, G-ALPHA-q, GAQ, SWS

Description: Anti GNAQ(Q209R) Mouse Monoclonal Antibody

Background: GNAQ is a protein that in humans encoded by the GNAQ gene. The GNAQ protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospholipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation.

Immunogen: A synthetic peptide from the internal region of GNAQ which includes the mutation of Q209R, human origin.

Applications: ELISA, WB, IHC

Recommended Dilutions: ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IHC: 1:50-1:100

Concentration: 1 mg/ml

Host: Mouse

Format: Liquid

Clonality: Monoclonal

Isotype:

Purity: Purified from ascites

Storage buffer:

Preservative: no

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Recognizes Q209R mutant, but not wild-type GNAQ of vertebrates.

Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles

Download Datasheet:

Western blot:

Western blot analysis of recombinant GNAQ(Q209R) and wildtype proteins. Purified His-tagged GNAQ(Q209R) protein (lane2) and corresponding wild-type protein (lane1) were blotted with Anti GNAQ(Q209R) monoclonal antibody (Cat. #26330).

Immunofluorescence:

Immunofluorescence of cells expressing GNAQ proteins with Anti GNAQ(Q209R) antibody. HEK293T cells were transfected with pCDNA3-GFP GNAQ(Q209R) plasmid, pCDNA3-GFP GNAQ(WT) plasmid, pCDNA3-GFP GNAQ(Q209L) plasmid or pCDNA3-GFP GNAQ(Q209P) plasmid, then fixed and stained with Anti GNAQ(Q209R) monoclonal antibody (Cat. #26330).

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