當(dāng)前位置：武漢紐斯特生物科技有限公司>>試劑盒>>Anti FBXW7(R479L) Mouse Monoclonal Antibody

Anti FBXW7(R479L) Mouse Monoclonal Antibody

返回列表頁

參考價: ￥ 4800

訂貨量: ≥1 臺

具體成交價以合同協(xié)議為準(zhǔn)

產(chǎn)品型號

品牌

廠商性質(zhì)生產(chǎn)商

所在地

在線詢價收藏產(chǎn)品查看聯(lián)系電話

聯(lián)系方式：樂亮明查看聯(lián)系方式

更新時間：2024-04-26 16:34:57瀏覽次數(shù)：93次

聯(lián)系我時，請告知來自環(huán)保在線

產(chǎn)品分類 品牌分類

  試劑盒

全部產(chǎn)品列表

  其他品牌

武漢紐斯特生物科技有限公司

經(jīng)營模式：生產(chǎn)廠家

商鋪產(chǎn)品：415條

所在地區(qū)：湖北武漢市

聯(lián)系人：樂亮明（經(jīng)理）

詢價 給他留言

產(chǎn)品簡介

FBXW7(R479L)[26347][100ul]CatalogNumber:26347GeneSymbol:FBW6

詳細(xì)介紹

FBXW7(R479L) [26347]
[100ul]

Catalog Number: 26347

Gene Symbol: FBW6; FBW7; FBXW7; FBX30; CDC4; SEL10

Description: Anti FBXW7(R479L) Mouse Monoclonal Antibody

Background: F-box/WD repeat-containing protein 7 is a protein that in humans is encoded by the FBXW7 gene. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. Mutations in this gene are detected in ovarian, breast and colorectal cancer cell lines, implicating the gene's potential role in the pathogenesis of human cancers.

Immunogen: A synthetic peptide from the internal region of FBXW7 which includes the mutation of R479L, human origin.

Applications: ELISA, WB

Recommended Dilutions:
ELISA: 1:1000-1:5000
WB: 1:500-1:1000

Concentration: 1 mg/ml

Host: Mouse

Format: Liquid

Clonality: Monoclonal

Isotype:

Purity: Purified from ascites

Storage buffer:

Preservative: no

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Recognizes R479L mutant, but not wild-type FBXW7 of vertebrates.

Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles

Download Datasheet:

Western blot:

Western blot analysis of recombinant FBXW7(R479L) and wildtype proteins. Purified His-tagged FBXW7(R479L) protein (lane 2) and corresponding wildtype protein (lane 1) were blotted with Anti FBXW7(R479L) monoclonal antibody (Cat. #26347).

Immunofluorescence:

Immunofluorescence of cells expressing FBXW7 proteins with Anti FBXW7(R479L) antibody. HEK293T cells were transfected with pCDNA3-GFP FBXW7(WT) plasmid (left column) or pCDNA3-GFP FBXW7(R479L) plasmid (right column), then fixed and stained with Anti FBXW7(R479L) monoclonal antibody (Cat. #26347).

其他推薦產(chǎn)品更多>>