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武漢紐斯特生物科技有限公司
武漢紐斯特生物科技有限公司
Anti GAPDH Rabbit Polyclonal Antibody
GAPDH [21012]
[100 µL]
| Catalog Number: 21012 |
| Gene Symbol: GAPDH |
| Description: Anti GAPDH Rabbit Polyclonal Antibody |
| Background: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, an important energy-yielding step in carbohydrate metabolism. Additional functions of GAPDH include acting as a uricil DNA glycosylase, activating transcription, binding RNA and involvement in nuclear RNA export, DNA replication and DNA repair. Fuethermore, expression of GAPDH is upregulated in liver, lung and prostate cancers. Moreover, GAPDH complexes with neuronal proteins implicated in human neuro-degenerative disorders including the β-Amyloid precursor, Huntingtin and other triplet repeat neuronal disorder proteins. |
| Immunogen: A synthetic peptide near the C-terminus of GAPDH of human origin |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA 1:100-1:5000 WB 1:100-1:2000 IHC 1:50-1:100 |
| Concentration: 0.2 mg/ml |
| Host: Rabbit |
| Format: Liquid |
| Clonality: Polyclonal |
| Isotype: IgG |
| Purity: Purified from serum |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ ａnd Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Anti GAPDH antibody recognizes GAPDH of vertebrates |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Download Datasheet: |
| Western blot: |
| EC-1 cell lysate was used for Western blot with anti GAPDH polyclonal antibody (Cat # 21012). |
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