Background: EYA2 (eyes absent homolog 2) functions as a tyrosine phosphatase that specifically dephosphorylates Tyr-142 of histone H2AX. EYA2 promotes efficient DNA repair and coactivates SIX1. Together with SIX1 and DACH2, EYA2 seems to be involved in myogenesis.
Immunogen: A synthetic peptide from the internal region of human EYA2.
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 59% glycerol Species
Species Reactivity: Anti-EYA2 antibody recognizes EYA2 of vertebrates.
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles
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Immunoprecipitation/Western blot:
Western blot analysis of recombinant full length EYA2 protein. Purified His-tagged EYA2 protein (Cat. #10195) was blotted with anti-EYA2 polyclonal antibody (Cat # 21128).