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武漢紐斯特生物科技有限公司
武漢紐斯特生物科技有限公司
Anti-Rac3 Mouse Monoclonal Antibody
Rac3_26064
[100 µL]
| Catalog Number: 26064 |
| Gene Symbol: RAC3 |
| Description: Anti-Rac3 Mouse Monoclonal Antibody |
| Background: Rac3 is a small GTPase of the Rho family that relays signals through direct interaction of GTP-bound Rac3 with downstream effector molecules. The Rac subfamily consists of Rac1, Rac2, and Rac3 proteins. While Rac1 is ubiquitously expressed, Rac2 and Rac3 are largely restricted to hematopoietic and neural tissues, respectively. Rac3 has biochemical properties that are closely related to Rac1. Both Rac1 and Rac3 have been implicated in the regulation of cell migration and invasion in human metastatic cancer. |
| Immunogen: A synthetic peptide near the C-terminus of human Rac3. |
| Applications: ELISA, WB, IHC, IP |
| Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:100-1:1000 IHC: 1:50-1:100 |
| Concentration: 1 mg/ml |
| Host: mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ ａnd Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Specifically recognizes Rac3, but not Rac1 or Rac2 of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Download Datasheet: |
| Western blot: |
| Western blot analysis of recombinant Rac3 proteins. Purified his-tagged Rac1 (Cat. #10101), Rac2 (Cat. #10184), and Rac3 (Cat. #10182) proteins were blotted with anti-Rac3 monoclonal antibody (Cat. #26064). |
| Publications: |
| 1. Cytoskeleton Volume 71, Issue 4, pages 257–272, April 2014 |
| 2. Neutrophil Methods and Protocols Methods in Molecular Biology Volume 1124, 2014, pp 251-268 |
| 3. Molecular and Cellular Neuroscience Volume 60, May 2014, Pages 10–25 |
| 4. The Journal of Immunology April 14, 2014 1301155 |
| 5. International Journal of Cancer Volume 135, Issue 11, pages 2493–2506, 1 December 2014 |
| 6. J Biol Chem. 2014 May 30;289(22):15244-58 |
| 7. Mol Cell Biol. 2014 Nov 15;34(22):4186-99 |
| 8. PLoS One. 2014 Sep 23;9(9):e108257 |
| 9. Cancer Lett. 2015 Jan 28;356(2 Pt B):382-91 |
| 10. Physiological ReportsPublished 24 October 2014Vol. 2no. e12175DOI: 10.14814/phy2.12175 |
| 11. Anticancer Research December 2014 vol. 34 no. 12 7111-7117 |
| 12. Cancer letters. March 1, 2015Volume 358, Issue 1, Pages 76–84. |
| 13. Integr Biol (Camb). 2014 Dec 24 |
| 14. Mol Neurobiol. 2015 Jan 24 |
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